Serveur d'exploration sur la COVID en France

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Survey of the Impact of COVID-19 on Oncologists' Decision Making in Cancer.

Identifieur interne : 000543 ( Main/Exploration ); précédent : 000542; suivant : 000544

Survey of the Impact of COVID-19 on Oncologists' Decision Making in Cancer.

Auteurs : Yüksel Ürün [Turquie] ; Syed A. Hussain [Royaume-Uni] ; Ziad Bakouny [États-Unis] ; Daniel Castellano [Espagne] ; Saadettin K L Çkap [Turquie] ; Gilberto Morgan [Suède] ; Rana R. Mckay [États-Unis] ; Kevin Pels [États-Unis] ; Andrew Schmidt [États-Unis] ; Deborah B. Doroshow [États-Unis] ; Fábio Schütz [Brésil] ; Laurence Albiges [France] ; Gilberto Lopes [États-Unis] ; James W F. Catto [Royaume-Uni] ; Solange Peters [Suisse] ; Toni K. Choueiri [États-Unis]

Source :

RBID : pubmed:32755479

Descripteurs français

English descriptors

Abstract

PURPOSE

To understand readiness measures taken by oncologists to protect patients and health care workers from the novel coronavirus (COVID-19) and how their clinical decision making was influenced by the pandemic.

METHODS

An online survey was conducted between March 24 and April 29, 2020.

RESULTS

A total of 343 oncologists from 28 countries participated. The median age was 43 years (range, 29-68 years), and the majority were male (62%). At the time of the survey, nearly all participants self-reported an outbreak in their country (99.7%). Personal protective equipment was available to all participants, of which surgical mask was the most common (n = 308; 90%). Telemedicine, in the form of phone or video encounters, was common and implemented by 80% (n = 273). Testing patients with cancer for COVID-19 via reverse transcriptase polymerase chain reaction before systemic treatment was not routinely implemented: 58% reported no routine testing, 39% performed testing in selected patients, and 3% performed systematic testing in all patients. The most significant factors influencing an oncologist's decision making regarding choice of systemic therapy included patient age and comorbidities (81% and 92%, respectively). Although hormonal treatments and tyrosine kinase inhibitors were considered to be relatively safe, cytotoxic chemotherapy and immune therapies were perceived as being less safe or unsafe by participants. The vast majority of participants stated that during the pandemic they would use less chemotherapy, immune checkpoint inhibitors, and steroids. Although treatment in neoadjuvant, adjuvant, and first-line metastatic disease was less affected, most of the participants stated that they would be more hesitant to recommend second- or third-line therapies in metastatic disease.

CONCLUSION

Decision making by oncologists has been significantly influenced by the ongoing COVID-19 pandemic.


DOI: 10.1200/GO.20.00300
PubMed: 32755479


Affiliations:


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Le document en format XML

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<name sortKey="Schutz, Fabio" sort="Schutz, Fabio" uniqKey="Schutz F" first="Fábio" last="Schütz">Fábio Schütz</name>
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<name sortKey="Albiges, Laurence" sort="Albiges, Laurence" uniqKey="Albiges L" first="Laurence" last="Albiges">Laurence Albiges</name>
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<name sortKey="Peters, Solange" sort="Peters, Solange" uniqKey="Peters S" first="Solange" last="Peters">Solange Peters</name>
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<name sortKey="Choueiri, Toni K" sort="Choueiri, Toni K" uniqKey="Choueiri T" first="Toni K" last="Choueiri">Toni K. Choueiri</name>
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<nlm:affiliation>Department of Medical Oncology, Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.</nlm:affiliation>
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<placeName>
<region type="state">Massachusetts</region>
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<series>
<title level="j">JCO global oncology</title>
<idno type="eISSN">2687-8941</idno>
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<date when="2020" type="published">2020</date>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Betacoronavirus (pathogenicity)</term>
<term>Clinical Decision-Making (MeSH)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (prevention & control)</term>
<term>Coronavirus Infections (transmission)</term>
<term>Coronavirus Infections (virology)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Infection Control (methods)</term>
<term>Infection Control (standards)</term>
<term>Infection Control (statistics & numerical data)</term>
<term>Infectious Disease Transmission, Patient-to-Professional (prevention & control)</term>
<term>Infectious Disease Transmission, Professional-to-Patient (prevention & control)</term>
<term>Male (MeSH)</term>
<term>Medical Oncology (methods)</term>
<term>Medical Oncology (standards)</term>
<term>Medical Oncology (statistics & numerical data)</term>
<term>Middle Aged (MeSH)</term>
<term>Neoplasms (diagnosis)</term>
<term>Neoplasms (therapy)</term>
<term>Oncologists (statistics & numerical data)</term>
<term>Pandemics (prevention & control)</term>
<term>Personal Protective Equipment (standards)</term>
<term>Personal Protective Equipment (statistics & numerical data)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Pneumonia, Viral (prevention & control)</term>
<term>Pneumonia, Viral (transmission)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Practice Patterns, Physicians' (standards)</term>
<term>Practice Patterns, Physicians' (statistics & numerical data)</term>
<term>Surveys and Questionnaires (statistics & numerical data)</term>
<term>Telemedicine (statistics & numerical data)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Betacoronavirus (pathogénicité)</term>
<term>Enquêtes et questionnaires (statistiques et données numériques)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections à coronavirus (prévention et contrôle)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Mâle (MeSH)</term>
<term>Oncologie médicale (méthodes)</term>
<term>Oncologie médicale (normes)</term>
<term>Oncologie médicale (statistiques et données numériques)</term>
<term>Oncologues (statistiques et données numériques)</term>
<term>Pandémies (prévention et contrôle)</term>
<term>Pneumopathie virale (prévention et contrôle)</term>
<term>Pneumopathie virale (transmission)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Prise de décision clinique (MeSH)</term>
<term>Prévention des infections (méthodes)</term>
<term>Prévention des infections (normes)</term>
<term>Prévention des infections (statistiques et données numériques)</term>
<term>Sujet âgé (MeSH)</term>
<term>Transmission de maladie infectieuse du patient au professionnel de santé (prévention et contrôle)</term>
<term>Transmission de maladie infectieuse du professionnel de santé au patient (prévention et contrôle)</term>
<term>Tumeurs (diagnostic)</term>
<term>Tumeurs (thérapie)</term>
<term>Types de pratiques des médecins (normes)</term>
<term>Types de pratiques des médecins (statistiques et données numériques)</term>
<term>Télémédecine (statistiques et données numériques)</term>
<term>Équipement de protection individuelle (normes)</term>
<term>Équipement de protection individuelle (statistiques et données numériques)</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Tumeurs</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Infection Control</term>
<term>Medical Oncology</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr">
<term>Oncologie médicale</term>
<term>Prévention des infections</term>
</keywords>
<keywords scheme="MESH" qualifier="normes" xml:lang="fr">
<term>Oncologie médicale</term>
<term>Prévention des infections</term>
<term>Types de pratiques des médecins</term>
<term>Équipement de protection individuelle</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en">
<term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr">
<term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Infectious Disease Transmission, Patient-to-Professional</term>
<term>Infectious Disease Transmission, Professional-to-Patient</term>
<term>Pandemics</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr">
<term>Infections à coronavirus</term>
<term>Pandémies</term>
<term>Pneumopathie virale</term>
<term>Transmission de maladie infectieuse du patient au professionnel de santé</term>
<term>Transmission de maladie infectieuse du professionnel de santé au patient</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en">
<term>Infection Control</term>
<term>Medical Oncology</term>
<term>Personal Protective Equipment</term>
<term>Practice Patterns, Physicians'</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en">
<term>Infection Control</term>
<term>Medical Oncology</term>
<term>Oncologists</term>
<term>Personal Protective Equipment</term>
<term>Practice Patterns, Physicians'</term>
<term>Surveys and Questionnaires</term>
<term>Telemedicine</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr">
<term>Enquêtes et questionnaires</term>
<term>Oncologie médicale</term>
<term>Oncologues</term>
<term>Prévention des infections</term>
<term>Types de pratiques des médecins</term>
<term>Télémédecine</term>
<term>Équipement de protection individuelle</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr">
<term>Tumeurs</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr">
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en">
<term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Clinical Decision-Making</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Prise de décision clinique</term>
<term>Sujet âgé</term>
</keywords>
</textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>
<b>PURPOSE</b>
</p>
<p>To understand readiness measures taken by oncologists to protect patients and health care workers from the novel coronavirus (COVID-19) and how their clinical decision making was influenced by the pandemic.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>An online survey was conducted between March 24 and April 29, 2020.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>A total of 343 oncologists from 28 countries participated. The median age was 43 years (range, 29-68 years), and the majority were male (62%). At the time of the survey, nearly all participants self-reported an outbreak in their country (99.7%). Personal protective equipment was available to all participants, of which surgical mask was the most common (n = 308; 90%). Telemedicine, in the form of phone or video encounters, was common and implemented by 80% (n = 273). Testing patients with cancer for COVID-19 via reverse transcriptase polymerase chain reaction before systemic treatment was not routinely implemented: 58% reported no routine testing, 39% performed testing in selected patients, and 3% performed systematic testing in all patients. The most significant factors influencing an oncologist's decision making regarding choice of systemic therapy included patient age and comorbidities (81% and 92%, respectively). Although hormonal treatments and tyrosine kinase inhibitors were considered to be relatively safe, cytotoxic chemotherapy and immune therapies were perceived as being less safe or unsafe by participants. The vast majority of participants stated that during the pandemic they would use less chemotherapy, immune checkpoint inhibitors, and steroids. Although treatment in neoadjuvant, adjuvant, and first-line metastatic disease was less affected, most of the participants stated that they would be more hesitant to recommend second- or third-line therapies in metastatic disease.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSION</b>
</p>
<p>Decision making by oncologists has been significantly influenced by the ongoing COVID-19 pandemic.</p>
</div>
</front>
</TEI>
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<DateCompleted>
<Year>2020</Year>
<Month>08</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised>
<Year>2020</Year>
<Month>08</Month>
<Day>18</Day>
</DateRevised>
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<Journal>
<ISSN IssnType="Electronic">2687-8941</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>6</Volume>
<PubDate>
<Year>2020</Year>
<Month>08</Month>
</PubDate>
</JournalIssue>
<Title>JCO global oncology</Title>
<ISOAbbreviation>JCO Glob Oncol</ISOAbbreviation>
</Journal>
<ArticleTitle>Survey of the Impact of COVID-19 on Oncologists' Decision Making in Cancer.</ArticleTitle>
<Pagination>
<MedlinePgn>1248-1257</MedlinePgn>
</Pagination>
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<Abstract>
<AbstractText Label="PURPOSE">To understand readiness measures taken by oncologists to protect patients and health care workers from the novel coronavirus (COVID-19) and how their clinical decision making was influenced by the pandemic.</AbstractText>
<AbstractText Label="METHODS">An online survey was conducted between March 24 and April 29, 2020.</AbstractText>
<AbstractText Label="RESULTS">A total of 343 oncologists from 28 countries participated. The median age was 43 years (range, 29-68 years), and the majority were male (62%). At the time of the survey, nearly all participants self-reported an outbreak in their country (99.7%). Personal protective equipment was available to all participants, of which surgical mask was the most common (n = 308; 90%). Telemedicine, in the form of phone or video encounters, was common and implemented by 80% (n = 273). Testing patients with cancer for COVID-19 via reverse transcriptase polymerase chain reaction before systemic treatment was not routinely implemented: 58% reported no routine testing, 39% performed testing in selected patients, and 3% performed systematic testing in all patients. The most significant factors influencing an oncologist's decision making regarding choice of systemic therapy included patient age and comorbidities (81% and 92%, respectively). Although hormonal treatments and tyrosine kinase inhibitors were considered to be relatively safe, cytotoxic chemotherapy and immune therapies were perceived as being less safe or unsafe by participants. The vast majority of participants stated that during the pandemic they would use less chemotherapy, immune checkpoint inhibitors, and steroids. Although treatment in neoadjuvant, adjuvant, and first-line metastatic disease was less affected, most of the participants stated that they would be more hesitant to recommend second- or third-line therapies in metastatic disease.</AbstractText>
<AbstractText Label="CONCLUSION">Decision making by oncologists has been significantly influenced by the ongoing COVID-19 pandemic.</AbstractText>
</Abstract>
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<LastName>Ürün</LastName>
<ForeName>Yüksel</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>Department of Medical Oncology, Ankara University School of Medicine, Ankara, Turkey.</Affiliation>
</AffiliationInfo>
<AffiliationInfo>
<Affiliation>Ankara University Cancer Research Institute, Ankara, Turkey.</Affiliation>
</AffiliationInfo>
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<LastName>Hussain</LastName>
<ForeName>Syed A</ForeName>
<Initials>SA</Initials>
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<Affiliation>Academic Unit of Oncology, University of Sheffield, Sheffield, United Kingdom.</Affiliation>
</AffiliationInfo>
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<ForeName>Ziad</ForeName>
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<Affiliation>Department of Medical Oncology, Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.</Affiliation>
</AffiliationInfo>
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<ForeName>Daniel</ForeName>
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<Affiliation>Medical Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.</Affiliation>
</AffiliationInfo>
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<LastName>Mckay</LastName>
<ForeName>Rana R</ForeName>
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<Affiliation>Moores Cancer Center, University of California San Diego, La Jolla, CA.</Affiliation>
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</AffiliationInfo>
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<Affiliation>Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.</Affiliation>
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<ForeName>Fábio</ForeName>
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<Affiliation>Clinical Oncology Department, BP - A Beneficência Portuguesa de São Paulo, São Paulo, Brazil.</Affiliation>
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<Affiliation>Department of Medical Oncology, Gustave Roussy Cancer Campus, Villejuif, France.</Affiliation>
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<Affiliation>Division of Hematology and Medical Oncology, Department of Medicine, Miller School of Medicine, University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL.</Affiliation>
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<LastName>Catto</LastName>
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<Affiliation>Oncology Department, Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland.</Affiliation>
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<Affiliation>Department of Medical Oncology, Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.</Affiliation>
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<name sortKey="Doroshow, Deborah B" sort="Doroshow, Deborah B" uniqKey="Doroshow D" first="Deborah B" last="Doroshow">Deborah B. Doroshow</name>
<name sortKey="Lopes, Gilberto" sort="Lopes, Gilberto" uniqKey="Lopes G" first="Gilberto" last="Lopes">Gilberto Lopes</name>
<name sortKey="Mckay, Rana R" sort="Mckay, Rana R" uniqKey="Mckay R" first="Rana R" last="Mckay">Rana R. Mckay</name>
<name sortKey="Pels, Kevin" sort="Pels, Kevin" uniqKey="Pels K" first="Kevin" last="Pels">Kevin Pels</name>
<name sortKey="Schmidt, Andrew" sort="Schmidt, Andrew" uniqKey="Schmidt A" first="Andrew" last="Schmidt">Andrew Schmidt</name>
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<country name="Espagne">
<region name="Communauté de Madrid">
<name sortKey="Castellano, Daniel" sort="Castellano, Daniel" uniqKey="Castellano D" first="Daniel" last="Castellano">Daniel Castellano</name>
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<country name="Suède">
<noRegion>
<name sortKey="Morgan, Gilberto" sort="Morgan, Gilberto" uniqKey="Morgan G" first="Gilberto" last="Morgan">Gilberto Morgan</name>
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</country>
<country name="Brésil">
<region name="État de São Paulo">
<name sortKey="Schutz, Fabio" sort="Schutz, Fabio" uniqKey="Schutz F" first="Fábio" last="Schütz">Fábio Schütz</name>
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</country>
<country name="France">
<noRegion>
<name sortKey="Albiges, Laurence" sort="Albiges, Laurence" uniqKey="Albiges L" first="Laurence" last="Albiges">Laurence Albiges</name>
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</country>
<country name="Suisse">
<region name="Canton de Vaud">
<name sortKey="Peters, Solange" sort="Peters, Solange" uniqKey="Peters S" first="Solange" last="Peters">Solange Peters</name>
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</affiliations>
</record>

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